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PressRelease) – Radon causes more deaths every year than any other household hazard including fires and carbon monoxide. Every home is required to have a smoke detector, but most homes have never been tested for radon. January is National Radon Action Month. According to radon mitigation contractor Jamey Gelina, “approximately 8 million U.S. homes have elevated radon levels.”

One in 15 homes across the U.S. has elevated radon levels. With as many as 21,000 deaths each year, radon exposure is second only to smoking in causing lung cancer deaths in the United States, according to the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention.

The only way to know whether radon exists in elevated levels in your home, and to protect your family from radon, is to test. EPA and National Safety Council are asking homeowners and renters to test their house for radon and learn how to protect families from radon gas.

In 2009, the World Health Organization, the United Nations, the President’s Cancer Panel, and the Health Physics Society have all called for stronger policies regarding radon risk reduction. Independent scientists from around the world have agreed that the threat is real and the WHO is calling for a reference level of 2.7 pCi/L of air for radon as compared to the US action level of 4.0. (These documents can be accessed at www.aarst.org)

Amid these growing concerns about the health risks of long-term exposure to indoor radon; EPA has designated January as National Radon Action Month. During National Radon Action Month Air Quality Control, in conjunction with EPA, will redouble our efforts to educate the public about the dangers of radon and what can be done to minimize the health risk from long-term exposure. As part of our efforts we will encourage the media and local health departments to help promote awareness of this national health problem.

Air Quality Control Agency, North America’s largest radon mitigation company is offering special discounts on radon testing kits and radon remediation services in honor of National Radon Action Month. You can contact their program director Jamey Gelina or a member of his staff by call 1-800-NO-RADON [1-800-667-2366.]

http://www.MitigationSystem.com

Source: http://www.1888pressrelease.com/radon-mitigation/radon-action-month/radon-gas-second-leading-lung-cancer-cause-according-to-jam-pr-178465.html

Graviola leaves contain anti-cancer substances called Annonaceous Acetogenin, which can kill cancer cells without disturbing the healthy cells in the human body. It turns out native plants that Amazon has the Latin name of Annona muricata, Commonly referred to Soursop.

Not just the fruit of Soursop (Annona muricata) has benefit as body protector. The results of Dr. Jerry McLaughlin of the United States, Soursop leaves are also anticancer. His research proves soursop leaf rid of various types of cancer cells, especially prostate, pancreatic and lung cancer. Leaf fruit Annonaceae family member that has an active compound killer cancer cells without damaging the body’s cells. Active compounds that improve the pumping of P-glycoprotein to be anticancer compounds resulting in alias chemotherapy. Dr Tirtawinata, fruit experts in Bogor, also recommends to consume 200 ml of boiled extract of leaves of soursop 2 times a day to rid the cancer from the body.

Some facts related to herbal properties of Graviola, are:

Effectively target and kill malignant cells in 12 types of cancers, including colon, breast, prostate, lung and pancreatic cancer.The tree compounds proved to 10,000 times stronger in slowing the growth of cancer cells from adriamycin, a commonly used chemotherapeutic drug!Catholic University of the South Korean reports that compounds extracted from tree Graviola selectively hunts down and kills only cancer cells. This does not harm healthy cells! Unlike chemotherapy, which will attack both healthy cells and cells infected with cancer (such as stomach and hair cells), leading to frequent damaging side effects of nausea and hair loss in cancer patients.A recent study at Purdue University found that leaves from the Graviola tree killed cancer cells among six human cell lines and is particularly effective against prostate, pancreatic and lung cancer.

Dose-been tested are:
10 Soursop leaves dark green washed, boiled in 3 cups water (600 cc), and left hanging until the remaining one cup of water (200 cc). Once cool, then strained and drunk every morning.In effect, the stomach will feel warm / hot, and sweating bodies. Keep in mind that herbal medicine will not cure directly, meaning that after taking a routine for 3-4 weeks a new effect is visible. The condition of the patient improves, activity can return, and after being reviewed lab / doctor turns out to dry the cancer cells, while other cells which grow (hair, nails, etc.) not at all disturbed.

Skin cancer is the most common type of cancer existing in the world. A lot of research and studies have been conducted for discovering and inventing the remedies for this serious disease.

It is a type of harmful, malignant growth affecting the skin of about one million people in a year in U.S.A. There are several causes such as severe sun burns, long term exposure to Ultra violet rays and a lot of others.

You need to do something about the condition of your skin as soon as you observe some of the warning signs. Some of the indications include change in the appearance of the skin such as a mole or sore that does not heal.

Skin cancer can occur in the following forms:

a)Basal Cell Carcinoma

b)Squamous Cell Carcinoma

c)Melanoma

– Basal Cell Carcinoma

This is referred to as the most common type of skin cancer. It does not spread to other parts of the body. It can invade other tissues surrounding the area.

– Squamous Cell Carcinoma

This type of cancer usually appears on the face, lips or rims of the ear. It starts from the squamous cells that are found in the tissues that forming the surface of the skin, respiratory and digestion tracts and lining of the hollow organs of your body. Reddish or Brownish wart lesions or nodules on forehead and cheeks.

– Melanoma

It is considered to be the most serious form of skin cancer as it tends to spread all over the body in a short period of time. The cancer may ooze bleed or itch. It is not painful.

There are several effective home remedies for treating skin cancer.

Here are some of the great remedies to try out:

– Coconut oil or butter remedy

Virgin coconut oil or butter is a good home remedy for skin care. It makes a good moisturizer and provides a good protective larger that locks in natural moisture as it has good solidifying property. You need to place the coconut butter in small lip palm or eye cream jars. You can also put it in a small sterilized jar.

– Aloe Vera

Aloe Vera is a great skin care remedy. It has been used effectively to treat dry skin, burns, insect bites and skin irritations. It is also good for acne, cuts and abrasions.

– Honey

Honey softens the skin and reduces wrinkles. It also adds to the glow of the skin.

– Ayurvedic Remedy

This is a holistic approach and does a lot of good to the skin.

– Skin cleansers

It cleanses the skin and removes dead cells from the surface of the skin. It will also remove the dust and dirt that chokes the pores on the skin. Try making cleansers at home via using vegetable oils, coconut oil and water. Sesame, palm and coconut oils make good cleansers. Seaweeds can also strengthen the immunity and healthy functions of the skin via providing the minerals required.

– Skin toners

Toning of the skin with lemon oil and lavender oil is good. You can also add vitamin C crystals as a preservative and antioxidant. When using witch hazel, make sure you combine it with moisturizers such as vitamin E and honey.

– Water

Drink at least six glasses of water to moisturize your skin.

All the above mentioned home remedies for skin cancer treatment are powerful and effective. You can try some of these to benefit from them.

However, you need to take to your doctor prior to using these methods to avoid any type of side effects that may occur.

Breast cancer is the most common form of cancer in women, and one of the most common types of cancer in general. It is estimated that one in seven women that live to age 90 will develop breast cancer. It is especially prevalent in some families, making the statistics a bit skewed. If you have a family history of breast cancer, your chances of developing the disease are much greater. Its therefore a good idea to stay especially vigilant for breast cancer symptoms. Breast cancer symptoms dont often manifest themselves until the cancer is already in its later stages of growth, and may have already metastasized to other more vital areas of the body. That is why it is so important for women to regularly get checked. Mammograms may be unpleasant, but late stage breast cancer symptoms are worse.

The most clear and common breast cancer symptom is of course a lump in your breast. It is important to keep in mind that not all lumps are cancerous. Most women will develop numerous lumps in their breasts throughout their lives; they are especially common during periods of rapid hormonal changes such as puberty, and menstruation. Some women will have more lumps than others.

A more severe breast cancer symptom will be pain in your breasts. A cancer that has grown large enough to impinge on nerves will be a noticeable lump in a self check or mammogram, so hopefully youll catch anything before it gets to the point of causing pain. If one or both of your breasts are in pain, again its important to keep in mind that you dont necessarily have breast cancer. During puberty and periods of hormone fluxes, tenderness of the breasts is common. Also pregnancy, and some medications can cause pain or tenderness in your breasts.

Even though most cases of breast cancer are diagnosed in women over 40, women in their teens and twenties are occasionally diagnosed as well. Most people dont know that about one percent of the cases are in men. Starting from puberty, it is a good idea to start checking yourself for lumps. Remember, during this period youre likely to find a lot of lumps that are harmless. With some experience and some consultation with your doctor, youll soon get an idea of the kinds of lumps that are normal, and the kinds of lumps that may be breast cancer symptoms.

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Erlotinib with brand name Tarceva was approved by US-FDA in May 14th 2013, for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC). This drug is intended for the patients whose tumors have epidermal growth factor receptor (EGFR) with gene substitution mutations. Tarceva was developed by Astellas Pharma Inc. in the US.

Lung cancer could be classified into two major categories. Small cell lung cancer, also known as oat cell carcinoma, accounts for about 15% of lung cancers and non small cell lung cancer (NSCLC) accounts for the majority of the lung cancer cases. Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy is increasingly being used both pre-operatively and post-operatively. The most common types of NSCLC are squamous cell carcinoma, large cell carcinoma, and adenocarcinoma, but there areseveral other types that occur less frequently, and all types can occur in unusual histological variants and as mixed cell-type combinations. Lung cancer in non-smokers is almost universally diagnosed with NSCLC, with a sizeable majority being adenocarcinoma. Adenocarcinoma of the lung is currently the most common type of lung cancer in “non- smokers”(especially never smokers). Adenocarcinoma account for approximately 40% of all the lung cancers. Squamous cell carcinoma (SCC) of the lung is more common in men than in women. It is closely correlated with a history of tobacco smoking, more so than most other types of lung cancer. The most prominent symptoms include persistent cough that may get worse over time, trouble breathing or shortness of breath, constant chest pain or discomfort, hoarseness, bloody phlegm or spit (sputum),infections such as bronchitis or pneumonia that won’t go away or that keep coming back , fatigue and weakness and unintentional weight loss.

Erlotinib is a reversible tyrosine kinase inhibitor, which inhibits epidermal growth factor receptor (EGFR). Erlotinib specifically targets the epidermal growth factor receptor (EGFR) (a tyrosine kinase), which is highly expressed and occasionally mutated in various forms of cancer. The drug binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. EGFR molecule dimerizes to form an active EGFRmoiety. The active dimeric form then use ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. By inhibiting the ATP, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated.

The drug was approved based on the results of a randomized, multicenter open-label trial comparing Erlotinib (n=86) to platinum-based doublet chemotherapy (n=88) in patients with metastatic NSCLC. In this study the subjects were specially selected whose tumors had EGFR exon 19 deletions or exon 21 (L858R) substitution mutations as determined by a clinical trial assay (CTA). Eligible patients were randomly assigned (1:1) to receive Erlotinib, 150 mg/day orally, or platinum-based doublet chemotherapy. Platinum-based doublet chemotherapy is the combination of platinum-based (cisplatin, carboplatin, which has platinum as their structural component) chemotherapy along with docetaxel, paclitaxel, vinorelbine, gemcitabine or irinotecan (which are non platinum based agents).Tumor samples from 134 patients were tested retrospectively with reference to the EGFR mutation test. The trial’s primary endpoint was investigator-assessed progression-free survival of the subjects (PFS). Secondary endpoints included overall survival (OS) and objective response rate (ORR) within the subjects. The median PFS was 10.4 months in the Erlotinib arm versus 5.2 months in the platinum-based chemotherapy arm. The median OS was 22.9 months in the Erlotinib arm and 19.5 months in the platinum-based chemotherapy arm. The ORR was 65 percent in the Erlotinib arm and 16 percent in the platinum-based chemotherapy arm. Thus Erlotinib (Tarceva) showed much promising effect compared to platinum-based doublet chemotherapy.

The recommended daily dose of Erlotinib for the treatment of NSCLC is 150 mg, which should be taken orally at least one hour before or two hours after eating a meal. Treatment should continue until disease progression or unacceptable toxicity is observed in subjects. The most common side effect of Erlotinib treated subjects include rash, diarrhea, asthenia, cough, dyspnoea and decreased appetite. The most frequent severe adverse reactions of Erlotinib treatment were rash and diarrhea.

The first line of therapy for any type of cancer plays a pivotal role for the cure of the disease. If the first line of therapy provides sufficient efficacious result, sometimes the cancer could be cured totally or in other cases it would progress very slowly. On November 2004, Erlotinib hydrochloride got approval by US-FDA (Tarceva tablets, OSI Pharmaceuticals Inc.) for treatment of patients with locally advanced or metastatic non-small cell lung cancer. Next on April, 2010 FDA approved Erlotinib for maintenance treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC).This was intended for the patients whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. In addition to these, approval of Erlotinib as first-line treatment of patients with metastatic non-small cell lung cancer on May 2013,make it a drug of choice for the treatment of all different stages of non-small cell lung cancer. Thus, Erlotinib has proven to be the most important drug for the treatment of a spectrum of non-small cell lung cancers.

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